SCHEMBL2015332

SCHEMBL2015332

CC(C)CCC(CC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 3/20 0.57
SLC1A2 P43004 3/20 0.57
SLC1A1 P43005 2/20 0.57
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
FOLH1 Q04609 2/20 0.40
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GABRR1 P24046 2/20 0.37
SLC7A5 Q01650 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17387490 1.00 SLC1A3 (0.57) SLC1A3SLC1A2SLC1A1GAAHTT
SCHEMBL7697914 0.82 FOLH1 (0.60) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL9115232 0.81 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL7094101 0.80 SLC1A3 (0.57) SLC1A3SLC1A2SLC1A1ADRA1ASLC7A5
SCHEMBL20548024 0.80 SLC1A3 (0.57) SLC1A3SLC1A2SLC1A1ADRA1ASLC7A5
SCHEMBL27809820 0.80 CHRM1 (0.65) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL21017198 0.80 CHRM1 (0.65) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL14312525 0.77 GABRR1 (0.44) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL2484602 0.77 FOLH1 (0.43) SLC1A3SLC1A2SLC1A1FOLH1CHRM1
SCHEMBL5378219 0.77 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088077-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) 2023-05-25 WO claimed
CN-214597573-U Detachable pipeline precise filtering device for carbamyl methyl-5-methylhexanoic acid 江西金丰药业有限公司 2021-11-05 CN claimed
CN-211636431-U Automatic feeding device for carbamyl methyl-5-methylhexanoic acid 江西金丰药业有限公司 2020-10-09 CN claimed
CN-211645086-U Carbamoylmethyl-5-methylhexanoic acid distillation plant 江西金丰药业有限公司 2020-10-09 CN claimed
CN-104557577-B High-purity (+)-Pregabalin and (-) preparation method of-Pregabalin 上海臣邦医药科技有限公司 2016-08-17 CN claimed
WO-2011077463-A1 PROCESS FOR PREPARING PREGABALIN AND ITS INTERMEDIATE MSN LABORATORIES LIMITED (IN) 2011-06-30 WO claimed
WO-2009004643-A2 AN IMPROVED PROCESS FOR PREPARATION OF (S)-PREGABALIN AND INTERMEDIATES THEREOF CADILA HEALTHCARE LIMITED (IN) 2009-01-08 WO claimed
EP-0828704-B1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER LAMBERT CO (US) 2002-03-13 EP claimed
EP-0828704-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1998-03-18 EP claimed
US-5616793-A Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid WARNER-LAMBERT COMPANY (US) 1997-04-01 US claimed
WO-1996038405-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1996-12-05 WO claimed
WO-2023088077-A1 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) 2023-05-25 WO disclosed
CN-112521299-B Preparation method of pregabalin intermediate 内蒙古永太化学有限公司 2022-08-16 CN disclosed
CN-112521299-B Preparation method of pregabalin intermediate 内蒙古永太化学有限公司 2022-08-16 CN disclosed
CN-214597573-U Detachable pipeline precise filtering device for carbamyl methyl-5-methylhexanoic acid 江西金丰药业有限公司 2021-11-05 CN disclosed
EP-0828704-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1998-03-18 EP disclosed
US-5629447-A Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid WARNER-LAMBERT COMPANY (US) 1997-05-13 US disclosed
US-5616793-A Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid WARNER-LAMBERT COMPANY (US) 1997-04-01 US disclosed
WO-1996038405-A1 METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID WARNER-LAMBERT COMPANY (US) 1996-12-05 WO disclosed
EP-0275101-A2 Novel peptidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1988-07-20 EP disclosed