Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547959 | 0.87 | HPGD (0.35) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL20547744 | 0.79 | MEN1 (0.34) | HPGDADORA2AADORA2BADORA3 | |
| SCHEMBL24686969 | 0.78 | HPGD (0.52) | HPGD | |
| SCHEMBL29386795 | 0.78 | HPGD (0.59) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL18992534 | 0.76 | KDM4E (0.52) | HPGDIMPDH2IMPDH1 | |
| SCHEMBL22434942 | 0.76 | KDM4E (0.52) | HPGDIMPDH2IMPDH1 | |
| Ammonia Solution, Strong SCHEMBL29779801 | 0.76 | KDM4E (0.52) | HPGDIMPDH2IMPDH1 | |
| SCHEMBL20548086 | 0.75 | TYMP (0.45) | HPGDADORA3ADORA1PAX8 | |
| SCHEMBL23487473 | 0.75 | TYMP (0.45) | HPGDADORA3ADORA1PAX8 | |
| SCHEMBL20547914 | 0.74 | ADORA2A (0.38) | HPGDADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |