Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547894 | 0.89 | MEN1 (0.41) | MEN1KMT2AHPGDADORA2AADORA2B | |
| SCHEMBL20547959 | 0.79 | HPGD (0.35) | HPGDADORA2AADORA2BADORA3 | |
| SCHEMBL20548168 | 0.79 | HPGD (0.37) | HPGDADORA2AADORA2BADORA3 | |
| SCHEMBL24686969 | 0.76 | HPGD (0.52) | HPGD | |
| SCHEMBL23487473 | 0.74 | TYMP (0.45) | HPGDADORA3 | |
| SCHEMBL20548086 | 0.74 | TYMP (0.45) | HPGDADORA3 | |
| SCHEMBL20547719 | 0.74 | STING1 (0.34) | — | |
| SCHEMBL22434942 | 0.74 | KDM4E (0.52) | MEN1KMT2AHPGD | |
| SCHEMBL18992534 | 0.74 | KDM4E (0.52) | MEN1KMT2AHPGD | |
| SCHEMBL20022057 | 0.74 | DNMT3B (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |