Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547891 | 0.80 | HDAC4 (0.39) | SCN9A | |
| SCHEMBL20547887 | 0.76 | NR3C2 (0.33) | — | |
| SCHEMBL20547561 | 0.76 | CCNK (0.39) | — | |
| SCHEMBL12869875 | 0.74 | SCN9A (0.38) | SCN9ADRD1 | |
| SCHEMBL486183 | 0.70 | SCN9A (0.44) | SCN9ADRD1 | |
| SCHEMBL486085 | 0.68 | DRD1 (0.39) | SCN9ADRD1 | |
| SCHEMBL20547563 | 0.68 | DGAT1 (0.37) | SCN9A | |
| SCHEMBL19205767 | 0.67 | DRD1 (0.47) | SCN9ADRD1 | |
| SCHEMBL13045975 | 0.66 | DRD1 (0.46) | DRD1 | |
| SCHEMBL28593290 | 0.66 | COMT (0.44) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603253-B | Heteroaryl phenylamino quinolines and analogs | 拜耳公司 | 2023-01-20 | — | — | CN | disclosed |
| US-11457629-B2 | Heteroarylphenylaminoquinolines and analogues | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-04 | — | — | US | disclosed |
| EP-3615523-B1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AG (DE) | 2021-07-14 | — | — | EP | disclosed |
| US-20200196602-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | US | disclosed |
| EP-3615523-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | Bayer Aktiengesellschaft (DE) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018197692-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200196602-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | PIK3C3, DDT, CYP4X1 | SCN9A 3573/4885DRD1 1408/4885 |
| US-11457629-B2 | Heteroarylphenylaminoquinolines and analogues | PIK3C3, CYP4X1, CYP1A2 | SCN9A 2682/4885DRD1 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.