Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008292 | 0.82 | MEN1 (0.77) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL6048481 | 0.80 | HPGD (0.63) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL1411294 | 0.80 | MEN1 (0.72) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL7685097 | 0.79 | MAPT (0.54) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL21590314 | 0.79 | MEN1 (0.83) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL656903 | 0.79 | MEN1 (0.77) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL1542356 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL8661871 | 0.79 | MEN1 (0.82) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL8401925 | 0.77 | KMT2A (0.79) | MEN1KMT2AMAPTMAPK1RAB9A | |
| SCHEMBL2351620 | 0.77 | MEN1 (0.79) | MEN1KMT2AMAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10118890-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10118890-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | AHR, ARSA, ALK | MEN1 2924/4885KMT2A 676/4885MAPT 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.