SCHEMBL1411294

SCHEMBL1411294

COC(=O)c1ccc(NC(=O)CON)cc1

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.72
KMT2A Q03164 5/20 0.72
MAPT P10636 5/20 0.61
RAB9A P51151 4/20 0.59
NPC1 O15118 1/20 0.59
LMNA P02545 4/20 0.57
HPGD P15428 3/20 0.57
ALDH1A1 P00352 3/20 0.57
MAPK1 P28482 1/20 0.56
KDM4E B2RXH2 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008292 0.86 MEN1 (0.77) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL1411400 0.86 RAB9A (0.76) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL18204569 0.83 STAT3 (0.55) MEN1KMT2AMAPTRAB9ALMNA
SCHEMBL656903 0.83 MEN1 (0.77) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL8661871 0.82 MEN1 (0.82) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL1411274 0.81 HPGD (0.68) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL2351620 0.81 MEN1 (0.79) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL8401925 0.81 KMT2A (0.79) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL18288680 0.80 KMT2A (0.66) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL20548265 0.80 MEN1 (0.66) MEN1KMT2AMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2056106-B1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO (JP) 2017-10-11 EP claimed
US-9340651-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-05-17 US claimed
WO-2015033743-A1 METHOD FOR PREPARING LABELED SUGAR CHAIN SAMPLE 住友ベークライト株式会社 (JP) 2015-03-12 WO claimed
EP-2518495-A2 Sugar chain-capturing substance and use thereof Sumitomo Bakelite Company, Ltd. (JP) 2012-10-31 EP claimed
US-20110089033-A1 METHOD OF PREPARING SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD OF ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-04-21 US claimed
EP-2295962-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN Sumitomo Bakelite Co., Ltd. (JP) 2011-03-16 EP claimed
WO-2009150834-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN 住友ベークライト株式会社 (JP) 2009-12-17 WO claimed
US-20090306291-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2009-12-10 US claimed
EP-2056106-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF Sumitomo Bakelite Company, Ltd. (JP) 2009-05-06 EP claimed
EP-2056106-B1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO (JP) 2017-10-11 EP disclosed
US-9714328-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY, LTD. (JP) 2017-07-25 US disclosed
EP-3096136-A1 COMPOSITION, METHOD FOR PREPARING SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYZING SUGAR CHAIN Sumitomo Bakelite Co.,Ltd. (JP) 2016-11-23 EP disclosed
US-20160327568-A1 COMPOSITION, METHOD FOR PREPARING SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2016-11-10 US disclosed
US-9340651-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-05-17 US disclosed
EP-2503332-A2 Sugar chain-capturing substance and use thereof Sumitomo Bakelite Company, Ltd. (JP) 2012-09-26 EP disclosed
US-20110089033-A1 METHOD OF PREPARING SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD OF ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-04-21 US disclosed
EP-2295962-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN Sumitomo Bakelite Co., Ltd. (JP) 2011-03-16 EP disclosed
WO-2009150834-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN 住友ベークライト株式会社 (JP) 2009-12-17 WO disclosed
US-20090306291-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2009-12-10 US disclosed
EP-2056106-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF Sumitomo Bakelite Company, Ltd. (JP) 2009-05-06 EP disclosed