Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548403 | 1.00 | GRIN2B (0.74) | GRIN2B | |
| SCHEMBL16600767 | 0.85 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16600762 | 0.85 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16600764 | 0.85 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601453 | 0.81 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601451 | 0.81 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601452 | 0.81 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601408 | 0.80 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601410 | 0.80 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601412 | 0.80 | GRIN2B (1.00) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461827-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-3036221-B1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2018-11-07 | — | — | EP | disclosed |