Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 17/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608160 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL30076111 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16601092 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16601041 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16608237 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16600963 | 0.81 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16600964 | 0.81 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16600965 | 0.81 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL20853643 | 0.76 | GRIN2B (0.83) | GRIN2BGRIN1 | |
| SCHEMBL16608474 | 0.73 | GRIN2B (0.72) | GRIN2BGRIN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036221-B1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | CADENT THERAPEUTICS INC (US) | 2018-11-07 | — | — | EP | claimed |