Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216545 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5517420 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL791333 | 0.73 | GAA (0.57) | KDM4EADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL29469069 | 0.73 | GAA (0.57) | KDM4EADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL3762294 | 0.72 | KMT2A (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31255734 | 0.72 | GAA (0.37) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31255732 | 0.72 | GAA (0.37) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1684395 | 0.71 | NPSR1 (0.41) | KMT2AALDH1A1HPGDHSD17B10PADI4 | |
| SCHEMBL5983378 | 0.70 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL21518326 | 0.70 | PDK2 (0.43) | MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398598-B1 | SULFONAMIDE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | HITGEN INC (CN) | 2022-04-06 | — | — | EP | disclosed |
| US-11149008-B2 | Sulfamide derivatives and preparation method and use thereof | HitGen, Inc. | 2021-10-19 | — | — | US | disclosed |
| US-20190031612-A1 | SULFAMIDE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | HITGEN LTD. (CN) | 2019-01-31 | — | — | US | disclosed |
| EP-3398598-A1 | SULFONAMIDE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Hitgen Ltd. (CN) | 2018-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149008-B2 | Sulfamide derivatives and preparation method and use thereof | HDAC6, HDAC1, HDAC11 | MEN1 3592/4885KMT2A 73/4885ALDH1A1 554/4885 |
| US-20190031612-A1 | SULFAMIDE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | HDAC6, HDAC1, HDAC11 | MEN1 3592/4885KMT2A 73/4885ALDH1A1 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.