SCHEMBL31255734

SCHEMBL31255734

O=C(NS)c1ccccc1B(O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.37
ENPP2 Q13822 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MPO P05164 1/20 0.35
HIF1A Q16665 1/20 0.35
HTT P42858 1/20 0.35
HPGD P15428 1/20 0.35
PLK1 P53350 1/20 0.35
ALOX15 P16050 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255732 1.00 GAA (0.37) GAAENPP2MEN1KMT2ATSHR
SCHEMBL29469069 0.82 GAA (0.57) GAAPOLBKDM4EPLK1
SCHEMBL791333 0.82 GAA (0.57) GAAPOLBKDM4EPLK1
SCHEMBL3784749 0.77 HPGD (0.62) MEN1KMT2ASMN1; SMN2ALDH1A1POLB
SCHEMBL4763194 0.77 PTGS2 (0.43) ENPP2KMT2ATSHRALDH1A1POLB
SCHEMBL5517420 0.76 MEN1 (0.44) GAAMEN1KMT2AALDH1A1POLB
SCHEMBL4744541 0.76 TSHR (0.43) KMT2ATSHRSMN1; SMN2HTTHPGD
SCHEMBL9325 0.74 NPC1 (0.55) GAAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL18586565 0.74 POLB (0.35) GAAENPP2MEN1KMT2ATSHR
SCHEMBL519802 0.74 ENPP2 (0.41) ENPP2MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081323-A Wear-resistant impact-resistant high polymer floor and preparation process thereof 洁玛新材料股份有限公司 2024-12-06 CN disclosed