Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013854 | 0.88 | ESR2 (0.63) | ESR2PDE3BPDE3ACYP2A6CYP2B6 | |
| SCHEMBL16192737 | 0.88 | ESR2 (0.63) | ESR2PDE3BPDE3ACYP2A6CYP2B6 | |
| SCHEMBL26820200 | 0.87 | ESR2 (0.52) | ESR2PTGS2MCL1ENPP3ENPP1 | |
| SCHEMBL28022262 | 0.83 | ESR2 (0.49) | ESR2PDE3BPDE3AHTR7MEN1 | |
| SCHEMBL27719211 | 0.81 | APP (0.57) | ESR2MCL1ESR1APPBACE1 | |
| SCHEMBL10341375 | 0.81 | ESR2 (0.55) | ESR2PDE3BPDE3AENPP3PDK2 | |
| SCHEMBL1481970 | 0.80 | ESR2 (0.52) | ESR2PTGS2MCL1CYP2A6CYP2B6 | |
| SCHEMBL29431901 | 0.80 | NPC1 (0.48) | ESR2MCL1ENPP3ENPP1HTR7 | |
| SCHEMBL76147 | 0.80 | NPC1 (0.48) | ESR2MCL1ENPP3ENPP1HTR7 | |
| SCHEMBL9876129 | 0.80 | CNR2 (0.51) | ESR2PTGS2ENPP3PDK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20180320071-A1 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | BPHL, KLK3, NEFM | ESR2 4022/4885PDE3B 972/4885PDE3A 1132/4885 |
| US-20180320071-A1 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | BPHL, KLK3, NEFM | ESR2 4022/4885PDE3B 972/4885PDE3A 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.