Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550352 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BPTGS1PDE4ASNCA | |
| SCHEMBL17866833 | 0.74 | MTNR1A (0.46) | MTNR1AMTNR1BPTGS1PDE4ASNCA | |
| SCHEMBL17866835 | 0.74 | MTNR1A (0.46) | MTNR1AMTNR1BPTGS1PDE4ASNCA | |
| SCHEMBL7551798 | 0.73 | MTNR1A (0.55) | MTNR1AMTNR1BMEN1KMT2ALOXL2 | |
| SCHEMBL25212573 | 0.69 | PTPN1 (0.51) | MEN1KMT2A | |
| SCHEMBL11283055 | 0.69 | PTPN1 (0.51) | MEN1KMT2A | |
| SCHEMBL11283056 | 0.69 | PTPN1 (0.51) | MEN1KMT2A | |
| SCHEMBL6905097 | 0.68 | PTPN1 (0.36) | — | |
| SCHEMBL6905099 | 0.68 | PTPN1 (0.36) | — | |
| SCHEMBL6253992 | 0.66 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1KMT2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |