Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552207 | 0.90 | KMT2A (0.50) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL20551861 | 0.87 | KMT2A (0.49) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL20552067 | 0.83 | KMT2A (0.52) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL31730842 | 0.82 | GPR84 (0.56) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL20551860 | 0.79 | KMT2A (0.51) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL20553123 | 0.79 | KMT2A (0.58) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL18029333 | 0.77 | KMT2A (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL1727642 | 0.77 | KMT2A (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL1114863 | 0.77 | KMT2A (0.62) | KMT2AKDM4ELMNAMAPTBLM | |
| SCHEMBL29855635 | 0.77 | KMT2A (0.62) | KMT2AKDM4ELMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621461-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | California Institute of Technology (US) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018204691-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-11-08 | — | — | WO | disclosed |