Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 19/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | SULT1A1 | P50225 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921658 | 1.00 | APP (1.00) | APPMAPTSULT1A1 | |
| SCHEMBL29409758 | 1.00 | APP (1.00) | APPMAPTSULT1A1 | |
| SCHEMBL29573398 | 1.00 | APP (1.00) | APPMAPTSULT1A1 | |
| SCHEMBL21566067 | 0.95 | APP (0.90) | APPMAPTSULT1A1 | |
| SCHEMBL2055208 | 0.91 | APP (0.84) | APPMAPTSULT1A1 | |
| SCHEMBL2055219 | 0.90 | APP (1.00) | APPMAPTSULT1A1 | |
| SCHEMBL2055217 | 0.86 | APP (0.76) | APPMAPTSULT1A1 | |
| SCHEMBL15604182 | 0.85 | APP (0.74) | APPMAPT | |
| SCHEMBL2055245 | 0.85 | APP (0.74) | APPSULT1A1 | |
| SCHEMBL2055248 | 0.85 | APP (0.74) | APPMAPTSULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160184461-A1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-06-30 | — | — | US | claimed |
| US-20140140932-A1 | Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-22 | — | — | US | claimed |
| EP-2699157-A2 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | The Regents of the University of California (US) | 2014-02-26 | — | — | EP | claimed |
| CN-103491870-A | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles | UNIV CALIFORNIA | 2014-01-01 | — | — | CN | claimed |
| WO-2012145169-A2 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-10-26 | — | — | WO | claimed |
| CN-101410393-B | Novel heteroaryl substituted benzothiazoles | ASTRAZENECA AB | 2012-01-25 | — | — | CN | claimed |
| US-20220202962-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-30 | — | — | US | disclosed |
| EP-3345545-B1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | UNIV CALIFORNIA (US) | 2021-10-20 | — | — | EP | disclosed |
| EP-3345545-B1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | UNIV CALIFORNIA (US) | 2021-10-20 | — | — | EP | disclosed |
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-05 | — | — | US | disclosed |
| US-10751428-B2 | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-25 | — | — | US | disclosed |
| US-10751428-B2 | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-25 | — | — | US | disclosed |
| US-20200246492-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-08-06 | — | — | US | disclosed |
| CN-101410393-A | Novel heteroaryl substituted benzothiazoles | ASTRAZENECA AB (SE) | 2009-04-15 | — | — | CN | disclosed |
| US-20090028787-A1 | Novel Heteroaryl Substituted Benzothiazoles | NAVIDEA BIOPHARMACEUTICALS, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20090028787-A1 | Novel Heteroaryl Substituted Benzothiazoles | NAVIDEA BIOPHARMACEUTICALS, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20090028787-A1 | Novel Heteroaryl Substituted Benzothiazoles | NAVIDEA BIOPHARMACEUTICALS, INC. | 2009-01-29 | — | — | US | disclosed |
| EP-1981883-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | AstraZeneca AB (SE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007086800-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007086800-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202962-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | APP 1/4885MAPT 23/4885SULT1A1 2430/4885 |
| US-10751428-B2 | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles | MAPT, PRNP, APP | APP 3/4885MAPT 1/4885SULT1A1 4844/4885 |
| US-20090028787-A1 | Novel Heteroaryl Substituted Benzothiazoles | APP, MAPT, PSEN1 | APP 1/4885MAPT 2/4885SULT1A1 439/4885 |
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | APP 1/4885MAPT 23/4885SULT1A1 2430/4885 |
| US-20140140932-A1 | Functionalized Magnetic Nanoparticles and Use in Imaging Amyloid Deposits and Neurofibrillary Tangles | MAPT, PRNP, APP | APP 3/4885MAPT 1/4885SULT1A1 4844/4885 |
| US-20160184461-A1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | MAPT, PRNP, APP | APP 3/4885MAPT 1/4885SULT1A1 4844/4885 |
| US-20200246492-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | APP 1/4885MAPT 23/4885SULT1A1 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.