⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792671 | 1.00 | — | — | |
| SCHEMBL8967183 | 0.72 | — | — | |
| SCHEMBL10016147 | 0.72 | — | — | |
| SCHEMBL24632033 | 0.67 | — | — | |
| SCHEMBL3391694 | 0.62 | — | — | |
| SCHEMBL806024 | 0.62 | — | — | |
| SCHEMBL12775273 | 0.62 | — | — | |
| SCHEMBL13122570 | 0.62 | — | — | |
| SCHEMBL18306916 | 0.62 | — | — | |
| SCHEMBL12465011 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130084245-A1 | PET MONITORING OF A-BETA-DIRECTED IMMUNOTHERAPY | WYETH LLC (US) | 2013-04-04 | — | — | US | disclosed |
| US-20120302603-A1 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120207679-A1 | Novel Heteroaryl Substituted Benzothiazoles | ASTRAZENECA AB (SE) | 2012-08-16 | — | — | US | disclosed |
| US-8163928-B2 | Heteroaryl substituted benzothiazoles | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |
| US-20090028787-A1 | Novel Heteroaryl Substituted Benzothiazoles | NAVIDEA BIOPHARMACEUTICALS, INC. | 2009-01-29 | — | — | US | disclosed |