⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016147 | 0.83 | — | — | |
| SCHEMBL18306916 | 0.72 | — | — | |
| SCHEMBL13792671 | 0.72 | — | — | |
| SCHEMBL2055282 | 0.72 | — | — | |
| SCHEMBL15003922 | 0.72 | — | — | |
| SCHEMBL4546305 | 0.61 | — | — | |
| SCHEMBL333801 | 0.58 | — | — | |
| SCHEMBL6747842 | 0.55 | — | — | |
| Iodoform SCHEMBL28140705 | 0.55 | — | — | |
| Iodoform SCHEMBL27906049 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215740-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-20180022704-A1 | PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-01-25 | — | — | US | disclosed |
| US-9809547-B2 | Process for the preparation of histamine H3 receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-07 | — | — | US | disclosed |
| US-20170057919-A1 | PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | US | disclosed |
| US-9518021-B2 | Process for the preparation of histamine H3 receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2016-12-13 | — | — | US | disclosed |
| US-9187408-B2 | Process for the preparation of protected L-alanine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-11-17 | — | — | US | disclosed |
| US-20140378701-A1 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-25 | — | — | US | disclosed |
| US-20140343279-A1 | PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-11-20 | — | — | US | disclosed |
| US-8748596-B2 | Process for the preparation of histamine H3 receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-10 | — | — | US | disclosed |
| US-20130066055-A1 | NEW BINDER-DRUG CONJUGATES (ADCS) AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-14 | — | — | US | disclosed |
| US-20110105762-A1 | TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF | NEREUS PHARMACEUTICALS, INC. (US) | 2011-05-05 | — | — | US | disclosed |
| EP-0519496-B1 | Thermosetting copolymers, silicon carbide-based fiber and processes for producing same | TONEN CORP (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0404503-B1 | Boron-containing, silicon nitride-based ceramic shaped body production process | TONEN CORP (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0389084-B1 | Process for producing a polyborosilazane | TONEN CORP (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5292830-A | Silane, silazane, boron block crosslinked copolymers | TONEN CORPORATION (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0519496-A1 | Thermosetting copolymers, silicon carbide-based fiber and processes for producing same | Tonen Corporation (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-5128286-A | BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY | TONEN CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5030744-A | Polyborosilazane and process for producing same | TONEN CORPORATION (JP) | 1991-07-09 | — | — | US | disclosed |
| EP-0404503-A1 | Boron-containing, silicon nitride-based ceramic shaped body production process | Tonen Corporation (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0389084-A2 | Process for producing a polyborosilazane | Tonen Corporation (JP) | 1990-09-26 | — | — | EP | disclosed |