Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2055302 | 1.00 | KMT2A (0.58) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL2055301 | 1.00 | KMT2A (0.58) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL2055298 | 0.98 | KMT2A (0.56) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL2055297 | 0.98 | KMT2A (0.56) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL12450195 | 0.93 | KMT2A (0.56) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL2055304 | 0.93 | KMT2A (0.56) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL64783 | 0.93 | KMT2A (0.65) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL15782634 | 0.92 | MEN1 (0.55) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL12847700 | 0.92 | KMT2A (0.50) | KMT2AMEN1TSHRKDM5ALMNA | |
| SCHEMBL12847856 | 0.92 | MEN1 (0.55) | KMT2AMEN1TSHRKDM5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889738-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889738-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-8163799-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163799-B2 | Amido-amine polymer compositions | GENZYME CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2008076242-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093857-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | PHPT1, PAM, PTH1R | KMT2A 1852/4885MEN1 127/4885TSHR 988/4885 |
| US-20120237470-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | PHPT1, PAM, PTH1R | KMT2A 1852/4885MEN1 127/4885TSHR 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.