SCHEMBL20554147

SCHEMBL20554147

O=C(O)N1CC(O)CC1CF

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
PIK3CD O00329 3/20 0.34
DPP4 P27487 5/20 0.33
DPP8 Q6V1X1 5/20 0.33
DPP9 Q86TI2 5/20 0.33
RIPK1 Q13546 1/20 0.33
VHL P40337 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15819175 1.00 ATM (0.40) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL20973171 1.00 ATM (0.40) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL28995810 1.00 ATM (0.40) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL21110975 0.82 MMP2 (0.35)
SCHEMBL22556879 0.82 MMP2 (0.35)
SCHEMBL2563460 0.82 ATM (0.41) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL3316717 0.82 ATM (0.41) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL21801954 0.82 ATM (0.41) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL2993204 0.82 ATM (0.41) ATMPIK3CDDPP4DPP8DPP9
SCHEMBL7657599 0.82 ATM (0.41) ATMPIK3CDDPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057045-A Fibroblast growth factor receptor kinase inhibitors 金耐特生物制药公司 2023-05-02 CN disclosed
EP-3401315-A1 FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF Guangzhou Henovcom Bioscience Co. Ltd. (CN) 2018-11-14 EP disclosed