⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446963 | 0.67 | — | — | |
| SCHEMBL451341 | 0.67 | — | — | |
| SCHEMBL152044 | 0.67 | — | — | |
| SCHEMBL8525145 | 0.64 | — | — | |
| SCHEMBL445395 | 0.62 | — | — | |
| SCHEMBL1515017 | 0.62 | — | — | |
| SCHEMBL1515054 | 0.62 | — | — | |
| SCHEMBL746155 | 0.62 | — | — | |
| SCHEMBL11890123 | 0.62 | — | — | |
| SCHEMBL969875 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163033-A1 | NOVEL COMPOUND, α-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | 国立研究開発法人量子科学技術研究開発機構 | 2023-08-31 | — | — | WO | disclosed |
| EP-4206200-A1 | NOVEL COMPOUND, ALPHA-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF | National Institutes for Quantum Science and Technology (JP) | 2023-07-05 | — | — | EP | disclosed |
| CN-115989029-A | Novel compound, alpha synuclein aggregate binding agent, and use thereof | 国立研究开发法人量子科学技术研究开发机构 | 2023-04-18 | — | — | CN | disclosed |
| EP-4023640-A1 | PHENYLIMIDAZOLE COMPOUND | Otsuka Pharmaceutical Factory, Inc. (JP) | 2022-07-06 | — | — | EP | disclosed |
| CN-113200962-A | Phenylimidazole compounds | 株式会社大塚制药工场 | 2021-08-03 | — | — | CN | disclosed |
| CN-108430977-B | Phenylimidazole compounds | 株式会社大塚制药工场 | 2021-06-08 | — | — | CN | disclosed |
| US-10570117-B2 | Phenylimidazole compound | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2020-02-25 | — | — | US | disclosed |
| US-20180354930-A1 | PHENYLIMIDAZOLE COMPOUND | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3401310-A1 | PHENYLIMIDAZOLE COMPOUND | Otsuka Pharmaceutical Factory, Inc. (JP) | 2018-11-14 | — | — | EP | disclosed |