Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558183 | 0.83 | ALDH1A1 (0.46) | HPGDEPHX1MAPTALDH1A1HTT | |
| SCHEMBL23249884 | 0.78 | HPGD (0.53) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL30853137 | 0.77 | HPGD (0.51) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL6513261 | 0.77 | EPHX1 (0.47) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL4523020 | 0.76 | HPGD (0.54) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL470530 | 0.76 | HPGD (0.54) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL387237 | 0.76 | HPGD (0.54) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL27478370 | 0.76 | HPGD (0.54) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL27552072 | 0.76 | USP2 (0.50) | HPGDRECQLEPHX1MAPTALDH1A1 | |
| SCHEMBL20558289 | 0.76 | HPGD (0.45) | HPGDRECQLEPHX1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018205948-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-11-15 | — | — | WO | disclosed |