SCHEMBL20564013

SCHEMBL20564013

CC1=CCOC1=O.COC(=O)c1ccoc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.40
PTPN6 P29350 1/20 0.40
PTPN11 Q06124 1/20 0.40
TSHR P16473 1/20 0.38
HTR7 P34969 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTK2 Q05397 1/20 0.35
RAB9A P51151 3/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
KCNK3 O14649 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL826948 0.80
Hydrochloric Acid SCHEMBL27597682 0.78 PTPN1 (0.50) PTPN1PTPN6PTPN11TSHRTDP1
Acetic Acid Methyl Ester SCHEMBL28147105 0.75 PTPN1 (0.47) PTPN1PTPN6PTPN11TSHRTDP1
Propionic Acid SCHEMBL28147107 0.71 TSHR (0.46) PTPN1PTPN6PTPN11TSHRTDP1
SCHEMBL908521 0.71
SCHEMBL8166741 0.67 MAPT (0.44) PTPN1PTPN6PTPN11TSHRTDP1
Benzene SCHEMBL4222994 0.66 CA12 (0.50) PTPN1PTPN6PTPN11TSHRPTK2
SCHEMBL12365087 0.66 RAB9A (0.44) TSHRTDP1RAB9AMAPTKMT2A
SCHEMBL8778642 0.66 PTPN1 (0.55) PTPN1PTPN6PTPN11PTK2RAB9A
SCHEMBL624090 0.65 CA12 (0.53) PTPN1PTPN6PTPN11TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3624596-A1 METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD International Flavors & Fragrances Inc. (US) 2020-03-25 EP disclosed
WO-2018213154-A1 METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-11-22 WO disclosed