Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 14/20 | 0.70 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10233695 | 1.00 | SLC6A9 (0.70) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL2056422 | 1.00 | SLC6A9 (0.70) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL2056353 | 1.00 | SLC6A9 (0.70) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL2056402 | 0.97 | SLC6A9 (0.75) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL2056369 | 0.97 | SLC6A9 (0.75) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL10234211 | 0.96 | SLC6A9 (0.66) | SLC6A9P2RX7CTSSCTSK | |
| SCHEMBL2054716 | 0.90 | SLC6A9 (0.76) | SLC6A9P2RX7CTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL4349938 | 0.87 | SLC6A9 (0.74) | SLC6A9P2RX7CTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL2098754 | 0.87 | SLC6A9 (0.74) | SLC6A9P2RX7CTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL4360720 | 0.87 | SLC6A9 (0.74) | SLC6A9P2RX7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163956-B2 | Inhibitors of GLYT1 transporters | MERCK SHARP & DOHME CORP. (US) | 2012-04-24 | — | — | US | disclosed |