Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056425 | 1.00 | SLC6A9 (0.48) | SLC6A9FLT1FLT4KDRMAPK1 | |
| SCHEMBL2056444 | 1.00 | SLC6A9 (0.48) | SLC6A9FLT1FLT4KDRMAPK1 | |
| SCHEMBL2056433 | 0.97 | SLC6A9 (0.51) | SLC6A9FLT1FLT4KDRMAPK1 | |
| SCHEMBL10232955 | 0.93 | SLC6A9 (0.48) | SLC6A9MAPK1RORCPDE2AGPR88 | |
| SCHEMBL10234061 | 0.93 | SLC6A9 (0.48) | SLC6A9MAPK1RORCPDE2AGPR88 | |
| SCHEMBL10234212 | 0.93 | SLC6A9 (0.48) | SLC6A9MAPK1RORCPDE2AGPR88 | |
| SCHEMBL2056427 | 0.91 | SLC6A9 (0.51) | SLC6A9MAPK1RORCPDE2APSMB11 | |
| SCHEMBL2056423 | 0.91 | SLC6A9 (0.51) | SLC6A9MAPK1RORCPDE2APSMB11 | |
| SCHEMBL2056422 | 0.84 | SLC6A9 (0.70) | SLC6A9 | |
| SCHEMBL2056353 | 0.84 | SLC6A9 (0.70) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163956-B2 | Inhibitors of GLYT1 transporters | MERCK SHARP & DOHME CORP. (US) | 2012-04-24 | — | — | US | disclosed |