Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 2/20 | 0.67 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.46 |
| ▸ | CLK1 | P49759 | 6/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314546 | 0.79 | CDK8 (0.77) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL15799700 | 0.76 | CDK8 (0.62) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL3761982 | 0.76 | DYRK1A (0.75) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL13745264 | 0.76 | CDK8 (0.72) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL12763233 | 0.76 | CDK8 (0.76) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL15799357 | 0.76 | CDK8 (0.58) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL17616963 | 0.75 | CDK8 (0.60) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL858219 | 0.75 | CDK8 (0.60) | CDK8CDK2CCNT1CCNA2CDK9 | |
| SCHEMBL20561681 | 0.74 | DYRK1A (0.43) | CDK8CDK2CCNT1CDK9AXL | |
| SCHEMBL20561552 | 0.74 | DYRK1A (0.43) | CDK8CDK2CCNT1CDK9AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018210661-A1 | HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2018-11-22 | — | — | WO | disclosed |