Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 1.00 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Incensole SCHEMBL20565149 | 1.00 | STAT3 (1.00) | STAT3METMEN1CNR2KMT2A | |
| Incensole SCHEMBL31471800 | 1.00 | STAT3 (1.00) | STAT3METMEN1CNR2KMT2A | |
| Incensole SCHEMBL13394034 | 1.00 | STAT3 (1.00) | STAT3METMEN1CNR2KMT2A | |
| Incensole SCHEMBL29369781 | 1.00 | STAT3 (1.00) | STAT3METMEN1CNR2KMT2A | |
| SCHEMBL13394030 | 0.86 | STAT3 (0.76) | STAT3METMEN1CNR2KMT2A | |
| SCHEMBL11451935 | 0.85 | STAT3 (0.74) | STAT3METMEN1CNR2KMT2A | |
| SCHEMBL11451938 | 0.85 | STAT3 (0.74) | STAT3METMEN1CNR2KMT2A | |
| SCHEMBL11451932 | 0.85 | STAT3 (0.74) | STAT3METMEN1CNR2KMT2A | |
| SCHEMBL17405153 | 0.82 | STAT3 (0.69) | STAT3MEN1KMT2APTAFRHIF1A | |
| SCHEMBL29516872 | 0.82 | STAT3 (0.69) | STAT3MEN1KMT2APTAFRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018213824-A2 | THERAPEUTICS AND METHODS TO TREAT ANGIOGENESIS RELATED PATHOLOGIES | Board of Supervisors for the University of Louisiana System (US) | 2018-11-22 | — | — | WO | disclosed |