SCHEMBL2056540

SCHEMBL2056540

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)C(O)[C@H]2O)cc1I

nearest known ligand 0.97

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.97
TK2 O00142 2/20 0.68
P2RY6 Q15077 5/20 0.64
P2RY14 Q15391 3/20 0.64
TK1 P04183 2/20 0.62
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
DNPH1 O43598 1/20 0.52
P2RY2 P41231 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18032577 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL2056544 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL3412420 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL2579194 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL12315567 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL3389861 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL97335 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL654674 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL97336 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1
SCHEMBL5165189 1.00 PYGM (0.97) PYGMTK2P2RY6P2RY14TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed