SCHEMBL2056541

SCHEMBL2056541

CC1OC(n2ccc(=O)[nH]c2=O)C(O)C1O

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.66
SLC28A2 O43868 1/20 0.66
SLC29A1 Q99808 1/20 0.66
SLC28A3 Q9HAS3 1/20 0.66
TSHR P16473 1/20 0.58
LMNA P02545 1/20 0.58
MAPT P10636 1/20 0.58
PMP22 Q01453 1/20 0.58
HBB P68871 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
P2RY2 P41231 12/20 0.57
P2RY14 Q15391 2/20 0.55
P2RY6 Q15077 9/20 0.54
P2RY4 P51582 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3945904 1.00 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
SCHEMBL13301520 1.00 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
SCHEMBL657542 1.00 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
SCHEMBL13669613 1.00 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
SCHEMBL13822077 1.00 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
Phosphoric Acid SCHEMBL3087812 0.94 P2RY2 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL28349923 0.93 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
Pyrophosphoric Acid SCHEMBL3095141 0.90 P2RY2 (0.67) P2RY2P2RY14P2RY6P2RY4
SCHEMBL14929497 0.90 SLC28A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3TSHR
SCHEMBL15059789 0.87 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20100143980-A1 SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF BALAGURUNATHAN KUBERAN 2010-06-10 US disclosed
WO-2008103618-A1 SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-08-28 WO disclosed
US-20070275988-A1 Transition state structure and inhibitors of thymidine phosphorylases INDUSTRIAL RESEARCH LIMITED (NZ) 2007-11-29 US disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143980-A1 SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF CSGALNACT1, ST3GAL3, FUT6 SLC28A1 2894/4885SLC28A2 2542/4885SLC29A1 2482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.