SCHEMBL20565609

SCHEMBL20565609

Brc1ccc(C2(c3ccccc3)C=Cc3c(ccc4cc(N(c5ccccc5)c5ccccc5)ccc34)O2)cc1

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808393 1.00 KDM4E (0.31) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL29457328 0.93 GPR84 (0.32)
SCHEMBL20565372 0.93 GPR84 (0.32)
SCHEMBL22169523 0.87
SCHEMBL20565903 0.86 KDM4E (0.32) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL30284250 0.85 SIRT2 (0.38) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL20565638 0.84 KDM4E (0.30) KDM4EMEN1NPC1ALDH1A1LMNA
SCHEMBL20565614 0.81 RARB (0.33) MEN1ALDH1A1MAPTKMT2A
SCHEMBL29457329 0.81 RARB (0.33) MEN1ALDH1A1MAPTKMT2A
SCHEMBL7122488 0.81 SIRT2 (0.37) KDM4EMEN1NPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3609976-B1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2022-08-24 EP disclosed
US-11248123-B2 Organic photochromic dye and uses thereof for dye sensitized solar cells COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2022-02-15 US disclosed
US-11248123-B2 Organic photochromic dye and uses thereof for dye sensitized solar cells COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2022-02-15 US disclosed
US-20200207991-A1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-07-02 US disclosed
US-20200207991-A1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-07-02 US disclosed
EP-3609976-A1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2020-02-19 EP disclosed
WO-2018215371-A1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2018-11-29 WO disclosed
EP-3406691-A1 ORGANIC PHOTOCHROMIC DYE AND USES THEREOF FOR DYE SENSITIZED SOLAR CELLS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2018-11-28 EP disclosed