Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 3/20 | 0.36 |
| ▸ | HK2 | P52789 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 3/20 | 0.33 |
| ▸ | FLT4 | P35916 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783419 | 1.00 | MEN1 (0.36) | MEN1KMT2AHK1HK2CNR1 | |
| SCHEMBL18783320 | 0.88 | HK2 (0.32) | MEN1KMT2AHK1HK2TBXAS1 | |
| SCHEMBL20565830 | 0.88 | HK2 (0.32) | MEN1KMT2AHK1HK2TBXAS1 | |
| SCHEMBL20565964 | 0.88 | HK2 (0.32) | MEN1KMT2AHK1HK2TBXAS1 | |
| SCHEMBL18783342 | 0.84 | CNR1 (0.36) | MEN1KMT2AHK1HK2CNR1 | |
| SCHEMBL20565682 | 0.84 | HK2 (0.34) | KMT2AHK1HK2ALDH1A1MAPT | |
| SCHEMBL18783323 | 0.84 | HK2 (0.34) | KMT2AHK1HK2ALDH1A1MAPT | |
| SCHEMBL20565694 | 0.84 | CNR1 (0.36) | MEN1KMT2AHK1HK2CNR1 | |
| SCHEMBL18802933 | 0.82 | TRPM5 (0.42) | MEN1KMT2ATBXAS1PTGISTRPM4 | |
| SCHEMBL16808503 | 0.82 | TRPM5 (0.42) | MEN1KMT2ATBXAS1PTGISTRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079685-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-11-28 | — | — | EP | claimed |
| EP-3079685-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-11-28 | — | — | EP | disclosed |