SCHEMBL2056641

SCHEMBL2056641

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)C(O)[C@H]2O)cc1O

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.72
TK2 O00142 2/20 0.66
SLC28A1 O00337 1/20 0.61
SLC28A2 O43868 1/20 0.61
SLC29A1 Q99808 1/20 0.61
SLC28A3 Q9HAS3 1/20 0.61
P2RY2 P41231 4/20 0.55
DNPH1 O43598 1/20 0.53
MAPT P10636 2/20 0.49
CDA P32320 1/20 0.49
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
LMNA P02545 1/20 0.48
PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18513005 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL12173959 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL2056643 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL451947 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL14928850 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL18513006 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL451948 1.00 PYGM (0.72) PYGMTK2SLC28A1SLC28A2SLC29A1
Pyrimidine SCHEMBL25285935 0.91 PYGM (0.64) PYGMTK2SLC28A1SLC28A2SLC29A1
Uridine SCHEMBL28289995 0.91 SLC28A1 (0.80) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL19272148 0.88 PYGM (0.56) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed