Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049660 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL5936414 | 0.84 | CYP3A4 (0.55) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL30881188 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL10034916 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL14448981 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL27613088 | 0.81 | CA12 (0.47) | ALDH1A1CYP3A4HSD17B10CA2CA12 | |
| SCHEMBL10035065 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL14812743 | 0.79 | POLB (0.44) | ALDH1A1CYP3A4PKMKDM4EMAPT | |
| SCHEMBL12383683 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP3A4PKMHSD17B10KDM4E | |
| SCHEMBL409154 | 0.79 | NOTUM (0.47) | ALDH1A1CYP3A4PKMHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | claimed |
| WO-2018216032-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-11-29 | — | — | WO | claimed |
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2020-12-15 | — | — | US | disclosed |
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2020-12-15 | — | — | US | disclosed |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | disclosed |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | disclosed |
| WO-2018216032-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | CYP1B1, CYP4B1, CYP1A1 | ALDH1A1 114/4885CYP3A4 17/4885PKM 1497/4885 |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | CYP1B1, CYP4B1, CYP1A1 | ALDH1A1 114/4885CYP3A4 17/4885PKM 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.