⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridazine SCHEMBL27741836 | 0.95 | — | — | |
| Pyridazine SCHEMBL27550221 | 0.95 | — | — | |
| Pyridazine SCHEMBL11423 | 0.94 | TSHR (0.42) | — | |
| Pyridazine SCHEMBL29471424 | 0.94 | — | — | |
| Pyridazine SCHEMBL5104 | 0.94 | — | — | |
| Pyridazine SCHEMBL21626119 | 0.89 | TSHR (0.39) | — | |
| Pyridazine SCHEMBL8874426 | 0.89 | TSHR (0.39) | — | |
| Pyridazine SCHEMBL21405425 | 0.89 | — | — | |
| Pyridazine SCHEMBL21222853 | 0.89 | — | — | |
| Pyridazine SCHEMBL6252071 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117835980-A | Tetrahydropyrazolopyridine analog ligand of NLRX1 and application thereof | 朗多生物制药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-110386922-A | Therapeutical active compound and its application method | 安吉奥斯医药品有限公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110372670-A | therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-109999041-A | Selective depression of the phenothiazine derivative to MALT1 protease | 亥姆霍兹慕尼黑中心-德国环境健康研究中心(GMBH) | 2019-07-12 | — | — | CN | disclosed |
| CN-109717202-A | A kind of Pesticidal combination | 江苏龙灯化学有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106558732-B | A kind of lithium-ion battery electrolytes and lithium ion battery | 比亚迪股份有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-103781481-B | Selective inhibition of MA L T1 protease by phenothiazine derivatives | 亥姆霍兹慕尼黑中心-德国环境健康研究中心 (GMBH) | 2018-12-14 | — | — | CN | disclosed |
| WO-2018215304-A1 | TETRACYCLIC PYRIDAZINE SULPHUR CONTAINING COMPOUNDS AND THEIR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-29 | — | — | WO | disclosed |
| CN-107960105-A | For insoluble and Soluble oxalate efficient oxalate-degrading enzyme of degrading | 凯普托杰姆有限责任公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-107531675-A | Therapeutical active compound and its application method | 安吉奥斯医药品有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-105475346-B | A kind of Pesticidal combination | 江苏龙灯化学有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-107206052-A | Method of enhancing blood brain barrier permeability and uses thereof | 中央研究院 | 2017-09-26 | — | — | CN | disclosed |
| CN-100548122-C | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-14 | — | — | CN | disclosed |
| CN-1878556-A | Combinations of drugs for the treatment of neoplasms | COMBINATORX INC (US) | 2006-12-13 | — | — | CN | disclosed |
| CN-1747722-A | Sugar-free oral transmucosal solid dosage forms and uses thereof | CEPHALON INC (US) | 2006-03-15 | — | — | CN | disclosed |
| CN-1251134-A | Neurotrophic factor NNT-1 | AMGEN INC (US) | 2000-04-19 | — | — | CN | disclosed |