Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263848 | 0.89 | ALDH1A1 (0.65) | ACP1ALDH1A1LMNAMAPTTACR1 | |
| SCHEMBL13960110 | 0.83 | ALDH1A1 (0.55) | ACP1ALDH1A1LMNATMPRSS4MAPT | |
| SCHEMBL449135 | 0.82 | ACP1 (0.60) | ACP1LMNANOTUMTMPRSS4MAPT | |
| SCHEMBL20568446 | 0.81 | ALDH1A1 (0.54) | ACP1ALDH1A1LMNAMAPTTACR1 | |
| SCHEMBL11786916 | 0.80 | ACP1 (0.61) | ACP1LMNANOTUMTMPRSS4MAPT | |
| SCHEMBL1925848 | 0.80 | ACP1 (0.61) | ACP1ALDH1A1LMNANOTUMTMPRSS4 | |
| SCHEMBL12513693 | 0.79 | MAPT (0.78) | ACP1LMNANOTUMTMPRSS4MAPT | |
| SCHEMBL13130515 | 0.79 | ALDH1A1 (0.58) | ACP1GAAALDH1A1LMNAMAPT | |
| SCHEMBL5448110 | 0.79 | ACP1 (0.60) | ACP1LMNANOTUMTMPRSS4MAPT | |
| Fluoride SCHEMBL11786925 | 0.79 | ACP1 (0.60) | ACP1ALDH1A1LMNANOTUMTMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601752-A | Novel inhibitors of MAP4K1 | 伊克诺斯科学公司 | 2021-04-02 | — | — | CN | disclosed |
| EP-3630778-A1 | NOVEL INHIBITORS OF MAP4K1 | Ichnos Sciences SA (CH) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215668-A1 | NOVEL INHIBITORS OF MAP4K1 | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-11-29 | — | — | WO | disclosed |