Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569237 | 1.00 | HDAC8 (0.60) | HDAC8DPP8DPP7HCRTR2NLN | |
| SCHEMBL20569359 | 0.81 | HDAC8 (0.53) | HDAC8DPP8DPP7HCRTR2NLN | |
| SCHEMBL20569358 | 0.81 | HDAC8 (0.53) | HDAC8DPP8DPP7HCRTR2NLN | |
| Hydrochloric Acid SCHEMBL20569597 | 0.80 | HDAC8 (0.47) | HDAC8DPP8DPP7NLN | |
| SCHEMBL4952073 | 0.79 | HDAC8 (0.74) | HDAC8DPP8DPP7NLNKMT2A | |
| Hydrochloric Acid SCHEMBL20569044 | 0.78 | HDAC8 (0.52) | HDAC8DPP8DPP7HCRTR2NLN | |
| Hydrochloric Acid SCHEMBL20569041 | 0.78 | HDAC8 (0.52) | HDAC8DPP8DPP7HCRTR2NLN | |
| Hydrochloric Acid SCHEMBL20569235 | 0.76 | HDAC8 (0.48) | HDAC8DPP8DPP7HCRTR2NLN | |
| Hydrochloric Acid SCHEMBL20569236 | 0.76 | HDAC8 (0.48) | HDAC8DPP8DPP7HCRTR2NLN | |
| SCHEMBL1358772 | 0.76 | HDAC8 (0.97) | HDAC8DPP8DPP7NLNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |