Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569358 | 1.00 | HDAC8 (0.53) | HDAC8DPP8DPP7NLNACACB | |
| Hydrochloric Acid SCHEMBL20569236 | 0.89 | HDAC8 (0.48) | HDAC8DPP8DPP7NLNACACB | |
| Hydrochloric Acid SCHEMBL20569235 | 0.89 | HDAC8 (0.48) | HDAC8DPP8DPP7NLNACACB | |
| Hydrochloric Acid SCHEMBL20569172 | 0.85 | HDAC8 (0.43) | HDAC8DPP8DPP7ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL20569169 | 0.85 | HDAC8 (0.43) | HDAC8DPP8DPP7ALDH1A1TSHR | |
| SCHEMBL20569239 | 0.81 | HDAC8 (0.60) | HDAC8DPP8DPP7NLNHCRTR2 | |
| SCHEMBL20569237 | 0.81 | HDAC8 (0.60) | HDAC8DPP8DPP7NLNHCRTR2 | |
| Hydrochloric Acid SCHEMBL20569044 | 0.77 | HDAC8 (0.52) | HDAC8DPP8DPP7NLNHCRTR2 | |
| Hydrochloric Acid SCHEMBL20569041 | 0.77 | HDAC8 (0.52) | HDAC8DPP8DPP7NLNHCRTR2 | |
| SCHEMBL8215788 | 0.77 | ACACB (0.42) | HDAC8ACACBKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |