Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.43 |
| ▸ | KDM6B | O15054 | 3/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892972 | 0.81 | KDM4C (0.52) | CA1CA2KDM4CKDM6BKDM4D | |
| SCHEMBL5768636 | 0.80 | MAPK1 (0.49) | KDM4CKDM6BKDM4DEGLN3 | |
| SCHEMBL30508987 | 0.79 | TSHR (0.50) | KDM4C | |
| SCHEMBL21647181 | 0.79 | TSHR (0.50) | KDM4C | |
| SCHEMBL27145744 | 0.79 | KDM4C (0.43) | KDM4CKDM6BKDM4DEGLN3DYRK1A | |
| SCHEMBL3194739 | 0.77 | MAPT (0.47) | CA1CA2KDM4CKDM4D | |
| SCHEMBL31734074 | 0.74 | KMT2A (0.58) | KDM4CKDM6BKDM4DEGLN3 | |
| SCHEMBL17045857 | 0.74 | KMT2A (0.58) | KDM4CKDM6BKDM4DEGLN3 | |
| SCHEMBL968912 | 0.74 | CA1 (0.64) | CA1CA2ADRA2C | |
| SCHEMBL5833311 | 0.72 | TSHR (0.49) | CA1CA2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |