SCHEMBL30508987

SCHEMBL30508987

COCC(=O)Nc1cnccc1O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 2/20 0.46
LMNA P02545 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KDM4C Q9H3R0 1/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
NOD2 Q9HC29 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21647181 1.00 TSHR (0.50) TSHRALDH1A1KMT2AGAALMNA
SCHEMBL5768636 0.79 MAPK1 (0.49) ALDH1A1GAALMNAKDM4C
SCHEMBL20569247 0.79 CA1 (0.45) KDM4C
SCHEMBL27144018 0.77 TSHR (0.70) TSHRALDH1A1KMT2AGAALMNA
SCHEMBL3194739 0.76 MAPT (0.47) TSHRALDH1A1KMT2AGAALMNA
SCHEMBL27145744 0.75 KDM4C (0.43) ALDH1A1GAAKDM4C
SCHEMBL30759275 0.74 NAMPT (0.43) RAB9A
SCHEMBL979159 0.73 MAPK1 (0.50) ALDH1A1GAALMNAKDM4CHPGD
SCHEMBL5833311 0.72 TSHR (0.49) TSHRKDM4CMAPTKDM4ERAB9A
SCHEMBL22075564 0.72 CYP3A4 (0.48) KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638899-B Preparation and application of aromatic compound with immunoregulation function 上海轶诺药业有限公司 2023-09-05 CN disclosed