Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108584 | 0.76 | MAPK1 (0.42) | HRH3LMNA | |
| SCHEMBL22748350 | 0.72 | LPL (0.47) | GAA | |
| SCHEMBL18682504 | 0.70 | NR5A1 (0.55) | LMNAPDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL24389487 | 0.70 | KDM4E (0.31) | HRH3KDM4E | |
| SCHEMBL13285053 | 0.70 | LPL (0.58) | KDM4ELMNA | |
| SCHEMBL15694455 | 0.69 | NR5A1 (0.58) | LMNATP53 | |
| SCHEMBL18682505 | 0.69 | NR5A1 (0.49) | PDE2APDE3BPDE3AP2RY12TP53 | |
| SCHEMBL18644047 | 0.69 | NR5A1 (0.58) | LMNATP53 | |
| SCHEMBL20831251 | 0.69 | PDE3B (0.54) | KDM4EPDK2PDE2APDE3BPDE3A | |
| SCHEMBL31150296 | 0.68 | PDK2 (0.39) | PDK2PDE2APDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |