Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349865 | 0.85 | MEN1 (0.46) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL20572269 | 0.81 | KDM4E (0.48) | KDM4EMEN1KMT2ACYP2D6 | |
| SCHEMBL27762347 | 0.79 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL28780266 | 0.79 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| Efetozole SCHEMBL21698044 | 0.77 | BRD4 (0.51) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| Efetozole SCHEMBL2109012 | 0.77 | BRD4 (0.51) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL10400587 | 0.76 | MEN1 (0.47) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| Efetozole SCHEMBL10996922 | 0.76 | BRD4 (0.50) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL27881082 | 0.76 | MEN1 (0.47) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL28705125 | 0.75 | ALDH1A1 (0.51) | KDM4EMEN1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |