Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 14/20 | 0.47 |
| ▸ | CCR3 | P51677 | 14/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722932 | 0.95 | HRH1 (0.48) | HRH1CCR3KCNH2EPHX2CYP2C9 | |
| SCHEMBL5109347 | 0.84 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL20569782 | 0.84 | GPR119 (0.53) | HRH3 | |
| SCHEMBL21722924 | 0.83 | EGFR (0.42) | HRH1CCR3KCNH2FFAR4 | |
| SCHEMBL20570794 | 0.82 | HRH1 (0.50) | HRH1CCR3KCNH2EPHX2FFAR4 | |
| SCHEMBL22462743 | 0.81 | HRH1 (0.49) | HRH1CCR3KCNH2EPHX2CYP2C9 | |
| SCHEMBL28542968 | 0.79 | GPR119 (0.55) | HRH3 | |
| SCHEMBL215117 | 0.78 | HRH1 (0.49) | HRH1CCR3KCNH2EPHX2HRH3 | |
| SCHEMBL27900147 | 0.78 | HRH1 (0.49) | HRH1CCR3KCNH2EPHX2CYP2C9 | |
| SCHEMBL4718927 | 0.78 | HRH1 (0.72) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634404-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018217809-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |