SCHEMBL20569899

SCHEMBL20569899

O=c1[nH]cc(SCCc2ccc(Cl)cc2)cc1O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 19/20 0.75
GPR84 Q9NQS5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20569629 0.92 DAO (0.71) DAO
SCHEMBL20570125 0.89 DAO (0.61) DAO
SCHEMBL20570156 0.87 DAO (0.76) DAO
SCHEMBL20570574 0.86 DAO (0.79) DAO
SCHEMBL14488039 0.86 DAO (1.00) DAO
SCHEMBL20569602 0.86 DAO (0.55) DAOGPR84
SCHEMBL20570332 0.83 DAO (0.52) DAOGPR84
SCHEMBL20570169 0.79 DAO (0.60) DAO
SCHEMBL14488165 0.77 DAO (1.00) DAO
SCHEMBL20569267 0.76 DAO (0.60) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018216823-A1 ALPHA-AMINO AMIDE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 2018-11-29 WO disclosed