Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569899 | 0.83 | DAO (0.75) | DAOGPR84 | |
| SCHEMBL20569602 | 0.82 | DAO (0.55) | DAOGPR84 | |
| SCHEMBL20569629 | 0.75 | DAO (0.71) | DAO | |
| SCHEMBL20570156 | 0.72 | DAO (0.76) | DAO | |
| SCHEMBL20570125 | 0.71 | DAO (0.61) | DAO | |
| SCHEMBL1929964 | 0.71 | MCL1 (0.51) | DAOMCL1BCL2A1GPR84KDM6B | |
| SCHEMBL11164633 | 0.70 | DYRK1A (0.64) | DYRK1AMCL1MAPT | |
| SCHEMBL20570574 | 0.70 | DAO (0.79) | DAO | |
| SCHEMBL20570300 | 0.70 | DAO (0.73) | DAOGPR84 | |
| SCHEMBL14488039 | 0.69 | DAO (1.00) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |