Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865441 | 0.85 | TSHR (0.42) | LMNA | |
| SCHEMBL17894518 | 0.83 | BRD4 (0.48) | BRD4MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9534958 | 0.80 | GSK3A (0.44) | — | |
| SCHEMBL14476612 | 0.79 | BRD4 (0.48) | BRD4MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15332214 | 0.78 | KMT2A (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20569246 | 0.78 | TLR8 (0.53) | BRD4FLT1KDRMEN1ALDH1A1 | |
| SCHEMBL20568998 | 0.76 | FLT1 (0.53) | FLT1KDRLMNASMN1; SMN2 | |
| SCHEMBL16581984 | 0.76 | HTT (0.44) | BRD4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5748758 | 0.76 | MCL1 (0.35) | FLT1KDRMEN1ALDH1A1KMT2A | |
| SCHEMBL20570323 | 0.75 | KCNH2 (0.49) | FLT1KDRMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |