Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569778 | 0.95 | TLR8 (0.55) | TLR8ARG1KCNH2FLT1KDR | |
| SCHEMBL6639388 | 0.90 | TLR8 (0.47) | TLR8ARG1KCNH2FLT1KDR | |
| SCHEMBL20569455 | 0.82 | KCNH2 (0.49) | TLR8KCNH2BRD4 | |
| SCHEMBL7508654 | 0.82 | MEN1 (0.51) | TLR8KCNH2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL20570323 | 0.79 | KCNH2 (0.49) | KCNH2FLT1KDRMEN1ALDH1A1 | |
| SCHEMBL20570174 | 0.79 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20570010 | 0.78 | BRD4 (0.41) | FLT1KDRMEN1ALDH1A1CYP1A2 | |
| SCHEMBL20572275 | 0.78 | KCNH2 (0.50) | KCNH2CYP2D6CYP2C19 | |
| SCHEMBL20568998 | 0.77 | FLT1 (0.53) | FLT1KDR | |
| SCHEMBL27658200 | 0.76 | TLR8 (0.67) | TLR8ARG1KCNH2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |