Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 11/20 | 0.47 |
| ▸ | RBP4 | P02753 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132020 | 0.87 | EPHX2 (0.65) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL20570577 | 0.85 | KDM1A (0.53) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL20570467 | 0.82 | EPHX2 (0.54) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL9902820 | 0.81 | EPHX2 (0.50) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL20571095 | 0.80 | EPHX2 (0.53) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL25414530 | 0.80 | EPHX2 (0.59) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL4259803 | 0.80 | EPHX2 (0.59) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL2946871 | 0.80 | EPHX2 (0.59) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL16418281 | 0.79 | EPHX2 (0.45) | EPHX2KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL20571363 | 0.76 | SCD (0.52) | EPHX2KDM4ELMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634404-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018217809-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |