Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | RBP4 | P02753 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | SCD | O00767 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946871 | 1.00 | EPHX2 (0.59) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL25414530 | 1.00 | EPHX2 (0.59) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL3132020 | 0.92 | EPHX2 (0.65) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL4170411 | 0.89 | RBP4 (0.65) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL2817662 | 0.88 | EPHX2 (0.55) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL2817663 | 0.88 | EPHX2 (0.55) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL19703353 | 0.86 | EPHX2 (0.53) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL19703355 | 0.86 | EPHX2 (0.53) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL25181872 | 0.84 | USP30 (0.53) | EPHX2RBP4TTRSCDKDM4E | |
| SCHEMBL31381205 | 0.83 | SCD (0.61) | EPHX2RBP4TTRSCDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118296-A1 | Heteroaromatic Compounds As Inhibitors Of Stearoyl-Coenzyme A Delta-9 Desaturase | MERCK FROSST CANADA LTD. (CA) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118296-A1 | Heteroaromatic Compounds As Inhibitors Of Stearoyl-Coenzyme A Delta-9 Desaturase | SCD, SCD5, SREBF1 | EPHX2 1001/4885RBP4 874/4885TTR 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.