Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567635 | 0.88 | SCN4A (0.51) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL20566659 | 0.83 | MAPT (0.43) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL24970320 | 0.82 | HTT (0.51) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL21896802 | 0.82 | SCN4A (0.50) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL29019508 | 0.78 | GAA (0.45) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL20503479 | 0.77 | GAA (0.48) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL20570582 | 0.77 | BCL9 (0.43) | SCN4AGAAMGLLBCL9CTNNB1 | |
| SCHEMBL22350699 | 0.76 | GAA (0.43) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL20503501 | 0.75 | GAA (0.42) | SCN4AGAAMGLLKMT2ACYP1A2 | |
| SCHEMBL31568215 | 0.75 | GAA (0.50) | GAAMGLLKMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018217805-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |