Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 7/20 | 0.42 |
| ▸ | MGLL | Q99685 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503501 | 0.82 | GAA (0.42) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL24970320 | 0.82 | HTT (0.51) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL21896802 | 0.79 | SCN4A (0.50) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL20570751 | 0.78 | SCN4A (0.46) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL20567635 | 0.77 | SCN4A (0.51) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL20503479 | 0.77 | GAA (0.48) | GAASCN4ABCL9CTNNB1MGLL | |
| SCHEMBL22350699 | 0.76 | GAA (0.43) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL20566659 | 0.75 | MAPT (0.43) | GAASCN4ABCL9CTNNB1FAAH | |
| SCHEMBL31568215 | 0.72 | GAA (0.50) | GAABCL9CTNNB1FAAHMGLL | |
| SCHEMBL20557088 | 0.71 | KMT2A (0.43) | GAABCL9CTNNB1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |