Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 5/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570798 | 0.85 | ERN1 (0.39) | TDP1ERN1ALDH1A1LMNAHPGD | |
| SCHEMBL22116362 | 0.79 | MAP4K4 (0.37) | TDP1MAP4K4TSHRALDH1A1LMNA | |
| SCHEMBL22116326 | 0.79 | MAP4K4 (0.37) | TDP1MAP4K4TSHRALDH1A1LMNA | |
| SCHEMBL9717633 | 0.75 | MAP4K4 (0.33) | MAP4K4 | |
| SCHEMBL9689045 | 0.73 | TDP1 (0.52) | TDP1ERN1ALDH1A1LMNAMAPT | |
| SCHEMBL24234318 | 0.72 | PTGDR2 (0.51) | TSHRLMNAPTGDR2MEN1KMT2A | |
| SCHEMBL22116371 | 0.71 | PTGDR2 (0.40) | MAP4K4PTGDR2PTGDRFFAR4 | |
| SCHEMBL4232553 | 0.71 | PTGDR2 (0.61) | TDP1TSHRMAPTPTGDR2PTGDR | |
| SCHEMBL20570322 | 0.71 | KMT2A (0.46) | TDP1ERN1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL697540 | 0.71 | MAP4K4 (0.53) | MAP4K4TSHRMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634404-A1 | PYRAZOLE MAGL INHIBITORS | Lundbeck La Jolla Research Center, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018217809-A1 | PYRAZOLE MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-11-29 | — | — | WO | disclosed |