Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728508 | 0.82 | KMT2A (0.42) | TDP1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28781871 | 0.81 | ALDH1A1 (0.44) | TDP1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL27673446 | 0.79 | CYP4F2 (0.41) | KMT2AMEN1 | |
| SCHEMBL21143488 | 0.79 | TDP1 (0.57) | TDP1ERN1KMT2AALDH1A1GAA | |
| SCHEMBL16600290 | 0.78 | CYP3A4 (0.44) | KMT2AALDH1A1MAPTGAAMEN1 | |
| SCHEMBL29177417 | 0.78 | MEN1 (0.50) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL29223015 | 0.78 | TDP1 (0.52) | TDP1ERN1KMT2AALDH1A1MAPT | |
| SCHEMBL27659144 | 0.78 | KMT2A (0.38) | TDP1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8861735 | 0.77 | KMT2A (0.57) | TDP1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL6093144 | 0.77 | TDP1 (0.55) | TDP1ERN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506709-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |